Year
Month
(Peer-Reviewed) Peripancreatic vascular involvement in patients with type 1 autoimmune pancreatitis
Meizi Li ¹, Xiaoyin Bai ¹, Kai Xu 徐凯 ², Xi Wu 吴晰 ¹, Tao Guo 郭涛 ¹, Qingwei Jiang 蒋青伟 ¹, Qiang Wang 王强 ¹, Shengyu Zhang ¹, Yingyun Yang ¹, Yunlu Feng 冯云路 ¹, Aiming Yang 杨爱明 ¹
¹ Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
中国 北京 中国医学科学院 北京协和医学院 北京协和医院消化内科 疑难重症及罕见病国家重点实验室
² Department of Radiology, Peking Union Medical College Hospital, Beijing, China
中国 北京 北京协和医院放射科
Hepatobiliary Surgery and Nutrition, 2021-05-13
Background

Type 1 autoimmune pancreatitis (AIP) is the pancreatic manifestation of IgG4-related disease. However, this benign disease can result in the peripancreatic vascular involvement (PVI) on occasion, which increases the difficulty of diagnosis and treatment of this clinical entity as well as for differentiating it from pancreatic malignancies.

Methods

We retrospectively reviewed the information on demographics, clinical presentation, laboratory, imaging and endoscopic findings of 101 hospitalized patients with type 1 AIP treated in our department. All the patients were divided into non-PVI and PVI groups according to the first hospitalized medical data. Univariate and multivariate analyses were performed to analyse the potential predictive parameter(s) of PVI in AIP patients.

Results

Among the 101 type 1 AIP patients, 52 (51.5%) exhibited PVI, with a male/female ratio 5.5:1. Their average age was 58.37±8.68 years old. Univariate analysis revealed that the location of pancreatitis lesions, including the pancreatic tail (P=0.010), the presence of splenomegaly (P=0.001) and the white blood cell (WBC) number in peripheral blood (P=0.020), were significantly associated with PVI. The location of pancreatitis lesions, including the pancreatic tail (P=0.023), and the presence of splenomegaly (P=0.010) were found to be independent predictors of the development of PVI by a multivariable regression analysis. A total of 18 out of 25 patients in PVI group who underwent corticosteroid treatment and no less than 6 months radiological follow-up showed improvement in vascular lesions, and no case exhibited exacerbation of PVI lesions during follow-up. Of 36 patients in non-PVI group who were followed up for no less than 6 months, only one case exhibited PVI.

Conclusions

This retrospective study demonstrated that type 1 AIP was associated with a high proportion of PVI. Pancreatic tail involvement and splenomegaly may predict the PVI in type 1 AIP. PVI lesions are reversible in a subset of patients.
Peripancreatic vascular involvement in patients with type 1 autoimmune pancreatitis_1
Peripancreatic vascular involvement in patients with type 1 autoimmune pancreatitis_2
Peripancreatic vascular involvement in patients with type 1 autoimmune pancreatitis_3
Peripancreatic vascular involvement in patients with type 1 autoimmune pancreatitis_4
  • High-resolution tumor marker detection based on microwave photonics demodulated dual wavelength fiber laser sensor
  • Jie Hu, Weihao Lin, Liyang Shao, Chenlong Xue, Fang Zhao, Dongrui Xiao, Yang Ran, Yue Meng, Panpan He, Zhiguang Yu, Jinna Chen, Perry Ping Shum
  • Opto-Electronic Advances
  • 2024-12-16
  • High performance laser induced plasma assisted ablation by GHz burst mode femtosecond pulses
  • Jingbo Yin, Yulong Zhao, Minghui Hong
  • Opto-Electronic Advances
  • 2024-12-16
  • Sequential harmonic spin–orbit angular momentum generation in nonlinear optical crystals
  • Yutao Tang, Zixian Hu, Junhong Deng, Kingfai Li, Guixin Li
  • Opto-Electronic Advances
  • 2024-12-16
  • Design, setup, and facilitation of the speckle structured illumination endoscopic system
  • Elizabeth Abraham, Zhaowei Liu
  • Opto-Electronic Science
  • 2024-12-13
  • Ultra-high-Q photonic crystal nanobeam cavity for etchless lithium niobate on insulator (LNOI) platform
  • Zhi Jiang, Cizhe Fang, Xu Ran, Yu Gao, Ruiqing Wang, Jianguo Wang, Danyang Yao, Xuetao Gan, Yan Liu, Yue Hao, Genquan Han
  • Opto-Electronic Advances
  • 2024-10-31
  • Advanced biological imaging techniques based on metasurfaces
  • Yongjae Jo, Hyemi Park, Hyeyoung Yoon, Inki Kim
  • Opto-Electronic Advances
  • 2024-10-31
  • Orthogonal matrix of polarization combinations: concept and application to multichannel holographic recording
  • Shujun Zheng, Jiaren Tan, Hongjie Liu, Xiao Lin, Yusuke Saita, Takanori Nomura, Xiaodi Tan
  • Opto-Electronic Advances
  • 2024-10-23
  • Streamlined photonic reservoir computer with augmented memory capabilities
  • Changdi Zhou, Yu Huang, Yigong Yang, Deyu Cai, Pei Zhou, Kuenyao Lau, Nianqiang Li, Xiaofeng Li
  • Opto-Electronic Advances
  • 2024-10-22
  • High-precision multi-focus laser sculpting of microstructured glass
  • Kang Xu, Peilin Huang, Lingyu Huang, Li Yao, Zongyao Li, Jiantao Chen, Li Zhang, Shaolin Xu
  • Opto-Electronic Advances
  • 2024-10-09
  • Multi-physical field null medium: new solutions for the simultaneous control of EM waves and heat flow
  • Sailing He, Ruili Zhang, Junbo Liang
  • Opto-Electronic Advances
  • 2024-09-30
  • Adaptive decentralized AI scheme for signal recognition of distributed sensor systems
  • Shixiong Zhang, Hao Li, Cunzheng Fan, Zhichao Zeng, Chao Xiong, Jie Wu, Zhijun Yan, Deming Liu, Qizhen Sun
  • Opto-Electronic Advances
  • 2024-09-29
  • Data-driven polarimetric approaches fuel computational imaging expansion
  • Sylvain Gigan
  • Opto-Electronic Advances
  • 2024-09-28



  • Experimental investigation of early assessment of corpora cavernosa fibrosis with two-dimensional shear wave elastography                                Propensity score matching study of 325 patients with spontaneous rupture of hepatocellular carcinoma
    About
    |
    Contact
    |
    Copyright © PubCard